The IDH wild-type tumors in their study were predominantly GBMs (15 out of 16), whereas in our study the IDH wild-type tumours did not demonstrate GBM features, though some of them (most likely captured early during the natural history of tumour development) had EGFR amplification and TERT mutation, which are molecular hallmarks of GBMs. The gene discussed is EGFR; the disease is neoplasm.