BRAF and neoplasm: Compared to BRAF wt patients, patients with BRAF mutations were more likely to exhibit poor differentiation (P = 0.030), advanced TNM stage (P = 0.001), larger/more invasive tumor (P = 0.019), higher lymph node metastasis rate (P = 0.004), and higher synchronous (P = 0.002) and metachronous metastasis rate (P = 0.016).