Furthermore, it is important to understand how metabolic GE is regulated in the absence of aberrant MYC. This is necessary, as aberrant STAT and NF-κB signaling networks have been described among others in diffuse large B-cell lymphoma (DLBCL) and Hodgkin’s lymphoma (HL) (reviewed by refs. 13,14). The gene discussed is SOAT1; the disease is Hodgkins lymphoma.