DNAH8 and amyotrophic lateral sclerosis: ALS-CSF caused significant atrophy, reflected by angulated myofibres and grouping of type 2 fibres in the extensor digitorum longus (EDL) muscle (as shown by ATPase staining at pH 9.4) in ALS-CSF-injected (ALS) rats compared with normal control (NC) rats (Fig. 1A,B).