Different mutations in the FBN1 gene lead to a wide range of diseases, such as Marfan syndrome (MFS), Weill–Marchesani syndrome, acromelic dysplasias, stiff skin syndrome and Marfanoid-progeroid-lipodystrophy (MPL) syndrome (Pepe et al., 2016). The gene discussed is FBN1; the disease is Marfan syndrome.