We also sought to validate the methylation status of CpG loci on INSR and KLF14 given that both genes have been implicated in T2D risk according to genome‐wide association studies.41 Similarly, Illumina analysis demonstrated associations with HMW adiponectin response that did not persist after correction for multiple testing (Figure S5, Supporting Information). Here, KLF14 is linked to type 2 diabetes mellitus.