APEX1 and cancer: In addition to the MMR, DNA repair genes such as APEX1 (OMIM: 107748), MUTYH (OMIM: 604933), OGG1 (OMIM: 601982), NUDT1 (OMIM: 600312), XRCC5 (OMIM: 194364), XPA (OMIM: 611153), and ERCC2 (OMIM: 126340) play a crucial role in repairing DNA mutations and thus preventing cancer development (Sancar, Lindsey‐Boltz, Unsal‐Kaçmaz, & Linn, 2004).