Prevalent AF, lung function (FEV1), IL-6 and vWF together explained about 14% of the reduced risk [(0.56–0.62/(0.56–1)*100] and cardiac markers (cTnT and NT-proBNP) explained a further 21% of the reduced risk [(0.62–0.70)/0.62–1)*100]. The gene discussed is TNNT2; the disease is atrial fibrillation.