Statistical significant difference was found between heatstroke, heat exhaustion, and the following laboratory tests: high glucose level (p = 0.004), high creatinine (p = <0.001), hyponatremia (p = 0.046), high BUN (p = 0.023), hypokalemia (p = 0.045), low platelets (PLT) (p = 0.003), low hemoglobin (Hb) (p = 0.037), and high white blood cell (CK) (p = 0.044). The gene discussed is GSTM1; the disease is Hyponatremia.