In a recent study of 23 patients with PC, 30 patients with pancreatitis, and 35 healthy individuals, a correlation was observed between increased serum concentrations of trypsinogen (PRSS) 2 levels and the presence of PC or pancreatitis, suggesting its possible usefulness as diagnostic biomarker for PC [62]. The gene discussed is GZMK; the disease is pachyonychia congenita.