TIMP1 and pachyonychia congenita: Another panel proposed for PC detection was based on serum CA19-9, apolipoprotein (Apo)-AIV, and TIMP1 and obtained a sensitivity of 86% and specificity of 90% in the differentiation of early-stage PC from pancreatitis, higher values than achieved using CA19-9 alone (71% and 90%, respectively) [15].