CCL2 and neoplasm: The higher mean expression level of Cxcl10 relative to that of Ccl2 or Ccl7 in the F4-T2 tumor in comparison with F5-T1 agrees with our analyses of the number of CD8+ versus ED1+ cells infiltrated in the two tumors, and with previous reports that Cxcl10 expression in the TME is associated with a higher level of T-cell infiltration [75].