By contrast, oral administration of 10 and 50 mg/kg SGE considerably prevented the losses in final body weight (F=6.270, p = 0.0137), carcass weight (F=6.862, p = 0.0103), and heart weight (F=3.452, p = 0.0654), wasting of adipose tissue (F=9.562, p = 0.0033) and skeletal muscle (F=8.001, p = 0.0062), and elevation of serum IL-6 (F=24.70, p < 0.0062) in CT-26 tumor-bearing mice, while SGE treatment did not restore appetite. Here, IL6 is linked to neoplasm.