In this guideline [22], a 12-week regimen of daily fixed-dose combination of sofosbuvir (400 mg)/velpatasvir (100 mg)/NS3 inhibitor voxilaprevir (100 mg) is one of the recommended retreatment-regimens in NS5A inhibitor DAA-experienced GT1 patients with or without compensated cirrhosis. The gene discussed is KRAS; the disease is Cirrhosis.