Furthermore, the molecular signature of CD30-negative PTCL-NOS partially overlapped with that of TFH cells, although the correlation was not as strong as that with AITLs [2], suggesting that the AITL spectrum may be wider than suspected, as a subset of CD30(-) PTCL-NOs may derive from, or be related to, AITL [2]. This evidence concerns the gene TNFRSF8 and angioimmunoblastic T-cell lymphoma.