In our field, nodal PTCLs (n-PTCLs) are the most frequently diagnosed, and these may be classified into three subgroups: angioimmunoblastic T-cell lymphoma (AITL), peripheral T-cell lymphoma without specific features (PTCL-NOS), and ALK-positive and ALK-negative anaplastic large T-cell lymphoma (ALCL). This evidence concerns the gene ALK and anaplastic large cell lymphoma.