The expression signature included genes encoding proteins involved in normal embryonic development, cell proliferation, tumor growth and invasion (FGF9, SEMA3C, EDNRA) [14–16], angiogenesis (ANGPT2) [17], cell cycle regulation (CDKN1A) [18], membrane signaling (TSPAN7, CAV2) [19, 20], WNT-pathway inhibitors (DKK3) [21, 22], complement system (C1QA) [23] and neurotransmitter regulation (SLC1A3, SCG2) [24, 25]. The gene discussed is DKK3; the disease is neoplasm.