Ferrandiz-Pulido et al. [21] in 67 PSCC cases found phospho-mTOR (activated mTOR) and phospho-elF4E (a downstream effector protein of mTOR) immunoexpression was significantly increased in PSCC compared to adjacent normal tissues and associated with lymph node metastasis (p=0.05 and p=0.006, respectively). Here, MTOR is linked to metastatic malignant neoplasm in the lymph nodes.