To do so, we used three established ovarian cancer cell lines with well-defined characteristics: Igrov-1 cells as a cisplatin-intermediate sensitive, EGFR-expressing cell line, A2780 cells as a cisplatin-sensitive, EGFR-negative cell line and cisplatin-resistant Skov-3 cells, exhibiting EGFR expression. The gene discussed is EGFR; the disease is ovarian carcinoma.