NEAT1 and viral infectious disease: Using immuno-staining, fluorescence in situ hybridization (FISH) and cellular fractionation, we investigated the effect of HDV replication on the localization of PSF, p54nrb, PSP1 and NEAT1. Furthermore, because stress shock caused by viral infection could affect NEAT1 accumulation, we also quantified NEAT1 levels in cell replicating the HDV RNA genome.