Downregulation of miR-1291 in renal cancer, miR-195-5p in bladder cancer, and miR-150 in pancreatic cancer leads to enhanced expression of their direct targets, GLUT1, GLUT3, and GLUT4 respectively, which thus results in glucose uptake and contributes to tumor progression58–60. This evidence concerns the gene SLC2A4 and familial pancreatic carcinoma.