Downregulation of miR-1291 in renal cancer, miR-195-5p in bladder cancer, and miR-150 in pancreatic cancer leads to enhanced expression of their direct targets, GLUT1, GLUT3, and GLUT4 respectively, which thus results in glucose uptake and contributes to tumor progression58–60. The gene discussed is SLC2A1; the disease is familial pancreatic carcinoma.