EP3 staining was not associated with tumor size (≤ 2 cm vs. > 2 cm, p = 0.394), primary lymph node metastasis (pN0 vs. pN1–3, p = 0.132) the histological subtype of the tumor (NST vs. non NST, p = 0.970), tumor grade (G1-G2 vs. G3, p = 0.944) or with the number of tumor foci (unifocal vs. more than one focus, p = 0.977). This evidence concerns the gene PTGER3 and neoplasm.