Overall, the level of HLTF expression was lower in tumours from patients than in cell lines (WT HLTF: 20.6 vs. 71.5, p = 9.3 × 10− 11 and I21R HLTF: 2.2 vs. 18.3, p = 2.8 × 10− 12, Wilcoxon rank-sum test; Fig. 3). This evidence concerns the gene HLTF and neoplasm.