Along with BRCA1 (FANCS) and BRCA2 (FANCD1), involved in hereditary breast/ovarian cancer (HBOC) syndrome, three other members of the FANC family have been associated with an increased risk of development of BrCa and/or ovarian cancer (OvCa), namely BRIP1 (FANCJ), PALB2 (FANCN) and RAD51C (FANCO) [41–44]. Here, BRCA2 is linked to Hereditary breast and ovarian cancer syndrome.