Considering that mutations in all these four FA members have been associated with risk for BrCa and/or OvCa [41,43,44], with mutations in BRIP1 and BRCA2 also associated with PrCa development [19,20,36], our report of mutations in RAD51C, FANCD2 and FANCI may increase to five the list of FA members involved in PrCa predisposition. Here, FANCI is linked to invasive breast carcinoma.