Considering that mutations in all these four FA members have been associated with risk for BrCa and/or OvCa [41,43,44], with mutations in BRIP1 and BRCA2 also associated with PrCa development [19,20,36], our report of mutations in RAD51C, FANCD2 and FANCI may increase to five the list of FA members involved in PrCa predisposition. This evidence concerns the gene BRIP1 and invasive breast carcinoma.