The BRIP1 mutation c.847T>C and the CHEK2 mutation c.695G>T were found in one of the 504 cancer cases (each) and the ATM mutations c.1595G>A and c.5750G>A were found in two cases (each) of the 710 healthy controls and in six and three cases, respectively, of the 504 cancer cases. This evidence concerns the gene CHEK2 and cancer.