The BRIP1 mutation c.847T>C and the CHEK2 mutation c.695G>T were found in one of the 504 cancer cases (each) and the ATM mutations c.1595G>A and c.5750G>A were found in two cases (each) of the 710 healthy controls and in six and three cases, respectively, of the 504 cancer cases. The gene discussed is BRIP1; the disease is cancer.