Hematopoietic progenitor stem cell (HPSC) mobilization and differentiation has been shown to be regulated by AnxA1 [63], e.g., AnxA1 deficiency results in increased cardiac necrosis, inflammation, hypertrophy and fibrosis resulting in exaggerated cardiac infarct size after eight days of myocardial infarction [63]. The gene discussed is ANXA1; the disease is myocardial infarction.