Our group has found ARID1A defective OCCC tumours can be targeted with the multikinase inhibitor dasatinib, mediated through addiction to the dasatinib target YES1 [9] and more recently a profound sensitivity to inhibition of the DNA repair kinase ATR, leading to premature mitotic entry, genomic instability, and apoptosis 24. Here, ARID1A is linked to neoplasm.