This hydrolase plays a role in the conversion ofarachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), and thereby,CYP4F2 reduces the fatty acid metabolite content and also is a preventing factorof lipotoxicity in fatty liver disease by regulation of the fatty acidmetabolism (Hardwick et al.,2010). The gene discussed is CYP4F2; the disease is fatty liver disease.