IFT80 and Jeune syndrome: Missense mutations in IFT80, which encodes an IFT-B2 subunit, have been identified in individuals with the skeletal ciliopathies Jeune asphyxiating thoracic dystrophy (JATD) as well as Verma-Naumoff syndrome (Baujat et al., 2013; Beales et al., 2007; Cavalcanti et al., 2011), but it is still unclear how these alterations affect protein function.