Our previous data revealed that Vav1, ectopically expressed in breast tumors in which positively correlates with follow‐up, regulates the transcription levels of genes encoding for Akt1 in breast tumor‐derived cells with a luminal B phenotype and for activators of the PI3K/Akt signaling in TNBC‐derived cells (Grassilli et al., 2014). The gene discussed is VAV1; the disease is breast neoplasm.