VAV1 and cancer: In recent years, aberrant expression of Vav1 has been reported in nonhematopoietic cancers (Bartolome et al., 2006; Fernandez‐Zapico et al., 2005; Hornstein et al., 2003; Lazer et al., 2009; Qi et al., 2015; Wakahashi et al., 2013; Zhu et al., 2017), in which this protein is involved in signal transduction processes correlated with tumor phenotype (Fernandez‐Zapico et al., 2005; Qi et al., 2015; Zhu et al., 2017).