ALB and breast carcinoma: For example, PLGA/goserelin acetate (Zoladex) was first approved by the FDA for treating prostate and breast cancer in 1989, PEGylated liposomal doxorubicin (Doxil) was approved for various types of cancer in 1995, and an albumin/paclitaxel system (Abraxane) was approved for breast cancer in 2005 [35].