The salivary EGF output in the severe SS group (6965.8 ± 6161.1 pg/10 min) was significantly lower than that in the mild SS group (12,275.7 ± 9420.0 pg/10 min) and the non-SS group (13,296.9 ± 7907.1 pg/10 min) (p < 0.05 and p < 0.01, respectively). Here, EGF is linked to synovial sarcoma.