Within the CNS, MIAT is reported to be expressed in neuronal populations in which the mature transcript is localised to the nucleus [108,109] and mediates its activity by binding to the splicing factors, SF1, QKI, SRSF1, and CELF, supporting a role for MIAT in regulating alternative splicing in schizophrenia [106,110,111]. This evidence concerns the gene MIAT and schizophrenia.