Other than MALAT-1 and PANDA, lncRNA Cancer susceptibility candidate 2 (CASC2) is significantly downregulated both in human osteosarcoma tissue and osteosarcoma cell lines MG-63, U2OS, SAOS2, and SOSP-9607 (p < 0.01; Table 1) [29]. This evidence concerns the gene CASC2 and osteosarcoma.