Other than MALAT-1 and PANDA, lncRNA Cancer susceptibility candidate 2 (CASC2) is significantly downregulated both in human osteosarcoma tissue and osteosarcoma cell lines MG-63, U2OS, SAOS2, and SOSP-9607 (p < 0.01; Table 1) [29]. Here, MALAT1 is linked to osteosarcoma.