INPP5D and infection: Experiments carried out using the virulent MBT strain support a permissive role for miR-155 in the infection of macrophages by mycobacteria: in fact, miR-155 maintains the survival of MBT-infected macrophages (through an inhibitory effect on SH2 domain-containing inositol 5-phosphatase 1 (SHIP1) and a consequent increase of phospho-AKT), providing a cellular niche favoring bacterial replication [55].