Given the opposite effects of miR-155 and miR-146a on T cell-mediated tumor immunity, with miR-155 inhibiting tumor growth and miR-146a favoring tumor development, it seemed of interest to evaluate the effect of a double miR-155 and miR-146a knockout on T cell-mediated anti-tumor response: in these mice, the anti-tumor response, as well as the IFNγ response resembled that observed in miR-155-deficient mice [78]. Here, IFNG is linked to neoplasm.