Glycogen synthase kinase 3β (GSK3β), a Ser/Thr protein kinase, is an important node; restricting its activation in epithelial cells can limit cancer progression and metastasis.47 Research has suggested that oxidative stress activates GSK3β, which is then involved in inducing the activation of Snail in a hypoxic environment, and the phosphorylation of GSK‐3β promotes the stabilization of Snail.48 The levels of GSK‐3β and phosphorylated GSK‐3β were measured to evaluate whether GSK‐3β is involved in VM formation and EMT via the ROS‐mediated pathway. Here, SNAI1 is linked to cancer.