CCl4 is a hepatotoxin and has been widely adopted for experimental induction of hepatic fibrosis.9 In hepatic fibrosis, the increased levels of AST, ALT, HA, LN, PCIII and Col IV indicate the ability of CCl4 to solubilize the lipid components and alter the ion channels of bio‐membranes. This evidence concerns the gene GPT and Hepatic fibrosis.