In addition, a lentiviral vector exhibited better transduction efficiency than a gammaretroviral vector in transducing T cells with a TCR targeting the Melan-A/MART-1 antigen [73], and a phase 2 trial of T cells transduced with a lentivirus to express MART-1 in patients with metastatic melanoma is ongoing. The gene discussed is MLANA; the disease is metastatic melanoma.