Furthermore, although the use of leukocyte-derived products such as lactate dehydrogenase (LDH) to discriminate between inflammatory and non-inflammatory fluids is well-established, the data herein suggest that additional leukocyte biomarkers such as lactotransferrin, alpha-enolase, and myeloperoxidase deserve evaluation as potential biomarkers of infection. This evidence concerns the gene ENO1 and infection.