FUS and amyotrophic lateral sclerosis: These include neuronal and glial inclusions comprising misfolded and phosphorylated TAR DNA-binding protein 43 kDA (pTDP-43) [10, 17, 35] and fused-in-sarcoma (FUS) protein [34], as well as dipeptide repeat pathology in C9ORF72 expansion-associated ALS (c9ALS) [54].