APC and adenocarcinoma: According to the presence of these mutations, the adenomas were subdivided into three groups: group 1 with APC mutations, comprising 20 adenomas, of which one was a hyperplastic polyp, 16 were adenomas and three were adenocarcinomas (all the mutations occurring at the level of the APC gene introduced premature stop codons); group 2 with CTNNB1 mutations occurred only in one adenoma with tubulovillous histology; group 3 with BRAF mutations occurred in three adenomas, with serrated histology [44].