TGFB1 and Familial prostate cancer: Examples include but are not limited to (i) CD-24 and EpCAM, which were described to be over- and under-represented, respectively, in isolated exosomes from breast cancer sera [118]; (ii) Glypican-1, a cell-surface proteoglycan reported as up-regulated in serum exosomes of patients with pancreatic cancer [119]; (iii) Survivin, whose levels were found increased in exosomes derived from prostate cancer when compared to those isolated from healthy donors [120]; and (iv) TGF-β1 and MAGE 3/6 (Melanoma associated Antigen 3/6), shuttled from exosomes isolated from ovarian cancer patients [121].