Positive staining for RAC1 was observed in 15 of 55 GCT tissues without recurrence and 14 of 20 GCT tissues with recurrence, and chi-square test suggested that the expression of RAC1 in GCT tissues with recurrence was significantly higher than that in GCT tissues without recurrence (P = 0.007) (Table 2). The gene discussed is RAC1; the disease is granular cell tumor.