GINS4 and urinary bladder cancer: It has been proposed that 60% of total genes in humans are regulated by miRNA, and it was recently discovered that a miRNA governs Sld5 expression and Sld5 was robustly expressed in human bladder cancer due to the reduced level of a candidate miRNA that interacts with the 3′-UTR of the SLD5 gene (Yamane et al., 2016).