MKI67 and cancer: The labeling index (LI) of Mcm7 in immunohistochemistry was more reliable than that of Ki-67 in several types of cancer and is strongly correlated to the tumor aggressiveness in astrocytoma and oral squamous cell carcinoma (Li et al., 2005; Facoetti et al., 2006b; Fujioka et al., 2009; Tamura et al., 2010; Choy et al., 2016).