DEFA1 and specific granule deficiency: Comparison of our data (Table S1 in Supplementary Material) to the previously published transcript dataset of one SGD patient (17) revealed that most proteins, such as DEFA1, MMP8, MMP9, TCN1, and others, of which mRNA transcripts have been previously shown to be reduced, were also absent in patient neutrophils on protein level [Table S1 in Supplementary Material and Ref.