Similarly, in human fibroblasts from frontotemporal degeneration (FTD) and amyotrophic lateral sclerosis (ALS) (FTD/ALS)30,31, the absolute copy number of c9orf72 mRNA was estimated at about 15 molecules/cell when measured by ddPCR and qPCR32. The gene discussed is C9orf72; the disease is amyotrophic lateral sclerosis.