Prostate cancers have a high propensity to metastasize into regional lymph nodes, and their expression of CX3CR1 correlates positively with the metastatic proclivity (Shulby et al., 2004; Andre et al., 2006; Marchesi et al., 2008; Castellana et al., 2009; Locatelli et al., 2010; Yao et al., 2014; Shen et al., 2016). The gene discussed is CX3CR1; the disease is Familial prostate cancer.