Pro‐inflammatory biomarker results are shown in FigureA. Compared with the S‐HFpEF cohort, the AD‐HFpEF cohort had higher levels of IL‐6 (4.14 pg/mL versus 1.71 pg/mL, P<0.001), TNF‐α (11.54 pg/mL versus 8.62 pg/mL, P=0.002), hs‐CRP (11.90 mg/dL versus 3.42 mg/dL, P<0.001) and PTX3 (3.08 ng/mL versus 1.27 ng/mL, P<0.001). This evidence concerns the gene PTX3 and Alzheimer disease.