RPGRIP1L and ciliopathy: Previous studies revealed a ciliopathy phenotype of Rpgrip1l−/− murine embryos, which die, at the latest around birth (Delous et al, 2007; Vierkotten et al, 2007; Besse et al, 2011; Gerhardt et al, 2013), whereas Rpgrip1l+/− mice are viable and healthy (Vierkotten et al, 2007; Besse et al, 2011; Gerhardt et al, 2013).