In a meta-analysis of microarray studies of four different dermatological diseases (dermatitis, acne, nickel allergy and psoriasis), MAP17 expression was correlated with a profile of cytokines (IFN-γ, IL-4, IL-6, IL-17A, IL-17F, and IL-22) that induced transcriptional downregulation of filaggrin [58]. Here, PDZK1IP1 is linked to psoriasis.