Among these genes, 15 genes, namely, CXCL10, VEGFA, TNF, TP63, FGFR1, CCL2, STAT1, CDK6, KIT, PTPRC, JUN, CD40, VEGFC, PRAME and KRAS have been reported to be associated with the regulation of cancer cell proliferation in hematological malignancies. The gene discussed is CD40; the disease is hematologic disorder.