Among these genes, 15 genes, namely, CXCL10, VEGFA, TNF, TP63, FGFR1, CCL2, STAT1, CDK6, KIT, PTPRC, JUN, CD40, VEGFC, PRAME and KRAS have been reported to be associated with the regulation of cancer cell proliferation in hematological malignancies. This evidence concerns the gene PRAME and hematologic disorder.