An interesting question would be whether Sall is expressed in C. fornicata nephridia during organogenesis, since Sall1 is necessary in mice to develop kidneys [37, 38] and the human SALL1 is mutated in patients with Townes–Brocks syndrome (TBS) [68], which produces among other symptoms abnormal kidney development. The gene discussed is SALL1; the disease is Townes-Brocks syndrome.