IDH1 and central nervous system cancer: In all tested glioma datasets, HOTAIR expression was not significantly associated with any other clinicopathological feature (patient age, sex, Karnofsky performance status [KPS], and exposure to radiotherapy or chemotherapy, except for associations with patient age in Phillips [24], Repository of Molecular Brain Neoplasia Data (REMBRANDT) and the French datasets, and associations with IDH mutation status in the French datatset; data not shown).